Development of Pancreatic Cancer Organoid Model for Studying Immune Response in Pancreatic Cancer
The importance of immune system in pancreatic ductal adenocarcinoma (PDAC) pathogenesis and therapy remains poorly understood largely due to the lack of effective model systems. Cell lines are not physiologic as they cannot recapitulate the cancer stroma and lose genetic heterogeneity over time. Gen...
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Format: | Thesis Electronic Book |
Language: | English |
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Ann Arbor :
ProQuest Dissertations & Theses,
2019
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