Development of Pancreatic Cancer Organoid Model for Studying Immune Response in Pancreatic Cancer

The importance of immune system in pancreatic ductal adenocarcinoma (PDAC) pathogenesis and therapy remains poorly understood largely due to the lack of effective model systems. Cell lines are not physiologic as they cannot recapitulate the cancer stroma and lose genetic heterogeneity over time. Gen...

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Bibliographic Details
Main Author: Yoo, Jin Woo
Corporate Author: Yale University School of Medicine
Format: Thesis Electronic Book
Language:English
Published: Ann Arbor : ProQuest Dissertations & Theses, 2019
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